Distinguishing between anticholinergic and cholinergic toxicity

These syndromes are a classic toxicology 101 topic. Review the information and fill in any knowledge gaps with our video lesson.

Kristin E. Fontes, MD FAAEM FACEP
Kristin E. Fontes, MD FAAEM FACEP
25th Jul 2022 • 1m read
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Tricyclic antidepressants, anti-Parkinson’s drugs, and some plants like jimson weed can cause anticholinergic toxicity, while exposure to insecticides can lead to cholinergic syndrome. In this lesson, you will review the anticholinergic and cholinergic syndromes as well as suitable antidotes like physostigmine, atropine, and pralidoxime.

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