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Chapter 1

Back to basics

Here, you’ll cover the relationship between a gas's fractional concentration and partial pressure, and calculations of partial pressures of dry versus humidified gases.
4 Lessons
10m 26s
Back to basics intro
27s
How to calculate the fractional concentration of gases in a mixture
3m 29s
Partial pressure and the alveolar air equation made simple
6m 30s
Back to basics quiz
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Chapter 2

Diffusion across the alveolar-capillary membrane

Learn about gas diffusion across the alveolar-capillary membrane. Factors discussed include the properties of the alveolar-capillary membrane and the gases within the alveoli.
6 Lessons
19m 23s
Diffusion across the alveolar-capillary membrane intro
30s
Simplifying Fick's law and lung gas exchange
3m 22s
What's the difference between diffusion- and perfusion-limited gas exchange?
4m 33s
How is RBC oxygen uptake affected by diffusion and perfusion?
4m 28s
What is diffusing capacity and why is it important?
6m 30s
Diffusion across the alveolar-capillary membrane quiz
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Chapter 3

Oxygen transport

Understand how oxygen is distributed between hemoglobin and the rest of the cell environment, and the factors affecting the equilibrium between free and hemoglobin-bound oxygen.
5 Lessons
16m 5s
Oxygen transport intro
34s
What makes RBCs so good at transporting oxygen?
3m 53s
What affects hemoglobin's oxygen affinity?
6m 23s
Calculating the total oxygen content of arterial blood
5m 15s
Oxygen transport quiz
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Chapter 4

Oxygen delivery to peripheral tissues

This chapter addresses the determinants of oxygen delivery to peripheral tissues. The concepts of oxygen content of the blood and cardiac output are discussed.
4 Lessons
7m 35s
Oxygen delivery to peripheral tissues intro
23s
What factors affect oxygen delivery?
2m 3s
Using the Fick equation to calculate the arteriovenous difference and cardiac output
5m 9s
Oxygen delivery to peripheral tissues quiz
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Chapter 5

The ventilation-perfusion relationship

Understand the relationship between regional lung ventilation and perfusion. Learn about why regional variations in ventilation and perfusion occur and the effect on gas exchange.
6 Lessons
11m 45s
The ventilation-perfusion relationship intro
31s
Everything you need to know about the ventilation-perfusion ratio
6m 16s
What's a physiological shunt?
1m 50s
What defines physiological dead space?
1m 15s
Asthma and ARDS as examples of altered ventilation-perfusion ratios
1m 53s
The ventilation-perfusion relationship quiz
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Chapter 6

Carbon dioxide removal

Learn about the main determinants of arterial PCO2, the relationship between carbon dioxide production and elimination, and the importance of alveolar and dead space ventilation.
4 Lessons
6m 21s
Carbon dioxide removal intro
38s
How are PaCO2 and minute ventilation related?
2m 9s
How is carbon dioxide transported in the blood?
3m 34s
Carbon dioxide removal quiz
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Chapter 7

Acid-base balance

This chapter covers the relationship between arterial PCO2, pH, and ventilation. You’ll cover the roles of ventilation and alterations in arterial PCO2 in adjusting arterial pH.
6 Lessons
20m 51s
Acid-base balance intro
39s
How does breathing help buffer the pH of blood?
5m 5s
How do I interpret a Davenport diagram?
3m 57s
Primary respiratory acid-base disorders
6m 12s
Primary metabolic acid-base disorders
4m 58s
Acid-base balance quiz
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Chapter 8

Case studies in blood gas analysis

This chapter provides two clinical cases for analysis, drawn from real-life clinical practice. These incorporate many of the principles covered in the preceding chapters.
5 Lessons
13m 29s
Case studies in blood gas analysis intro
32s
Case 1—What's in a number?
5m 58s
Case 2 —Now that's teamwork
5m 47s
Case studies in blood gas analysis quiz
Quiz
Blood Gas Analysis Essentials outro
1m 12s
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Teachers of this course
Image of Michael A. Grippi, MD
Michael A. Grippi, MD
Michael is Vice Chairman in the Department of Medicine and Associate Professor of Medicine in the Pulmonary, Allergy, and Critical Care Division at the Perelman School of Medicine, University of Pennsylvania, USA.
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