Timestamped Show Overview
01:29 The link between caffeinated coffee and atrial ectopy
03:34 Exploring financial connections between cardiologists and biopharmaceutical manufacturers
06:22 Phase 3 trial of sotatercept to treat pulmonary arterial hypertension
08:51 The risks connected with subclinical coronary atherosclerosis
What are the latest cardiology studies?
In this randomized case-crossover study, we'll explore whether caffeinated coffee affects premature atrial contractions (PACs) and ventricular contractions (PVCs) in healthy adults.
"During the study, it was found that caffeinated coffee was not associated with premature atrial contractions."
Marcus GM et al. Acute effects of coffee consumption on health among ambulatory adults. N Engl J Med 2023 Mar 23; 388:1092. (https://doi.org/10.1056/NEJMoa2204737)
Examine the Open Payments Program (OPP) data, revealing trends in industry payments to cardiologists from 2014 to 2019, including the necessity for transparency.
"It's absolutely necessary to have transparency in these financial relationships, and the study sheds light on the extent of payments and the types of payments being made."
Zhang R et al. Trends in industry payments to cardiologists from 2014 to 2019. Circ Cardiovasc Qual Outcomes 2023 Mar 17; [e-pub]. (https://doi.org/10.1161/CIRCOUTCOMES.122.009820)
Sotatercept has shown promising results in improving the six-minute walk distance of individuals with pulmonary arterial hypertension (PAH) but it’s associated with several side effects and more research is required before it can be considered a first-line therapy.
"The primary endpoint of a six-minute walk distance improved by a median of 34 meters in those treated with sotatercept compared with only 1 meter in the placebo group."
Hoeper MM et al. Phase 3 trial of sotatercept for treatment of pulmonary arterial hypertension. N Engl J Med 2023 Mar 6; [e-pub]. (https://doi.org/10.1056/NEJMoa2213558)
Discover how subclinical coronary atherosclerosis detectable computed tomographic angiography (CTA) can pose a significant risk for myocardial infarction (MI) in asymptomatic middle-aged men and women in a Danish cohort.
"Extensive or obstructive subclinical atherosclerosis conveys substantial excess risk for myocardial infarction."
Fuchs A et al. Subclinical coronary atherosclerosis and risk for myocardial infarction in a Danish cohort: A prospective observational cohort study. Ann Intern Med 2023 Mar 28; [e-pub]. (https://doi.org/10.7326/M22-3027)
Join us for this informative overview of contemporary research, as we break down complex medical concepts into digestible nuggets of knowledge, suitable for both medical students and healthcare professionals eager to keep up-to-date in cardiology.