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state of regional lung ventilation unaccompanied by blood flow—physiological dead space.",{"id":215,"name":216},1,"Course previews",[218,228,233,238,245],{"type":219,"data":220},"video",{"readDurationInSeconds":221,"video":222},97,{"platform":223,"name":212,"url":224,"size":225},"YouTube","https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=tzHGlaFy0xk",{"width":226,"height":227},200,113,{"type":229,"data":230},"free_text",{"readDurationInSeconds":231,"text":232},11.2,"\u003Cp> \u003Cstyle type=\"text\u002Fcss\">\u003C!--td {border: 1px solid #ccc;}br {mso-data-placement:same-cell;}--> \u003C\u002Fstyle> \u003C\u002Fp>\u003Cp>An abnormal ventilation-perfusion relationship can be seen where there are alveolar units with ventilation, but no persistent perfusion. In this video, from our Blood Gas Analysis Essentials course, you'll learn about the pathophysiologic consequences of a functional state of regional lung ventilation unaccompanied by blood flow—physiological dead space.\u003C\u002Fp>",{"type":229,"data":234},{"readDurationInSeconds":235,"title":236,"text":237},16.533333333333335,"Join our Blood Gas Analysis Essentials course now!","\u003Cp>Master arterial blood gas analysis based on an understanding of relevant physiological principles. You’ll cover the crucial factors that determine the oxygenation of blood in the lungs, as well as oxygen transport and delivery to peripheral tissues. Learn about the interplay between blood gas and acid-base analysis, and how carbon dioxide affects arterial pH. This course complements our \u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fcourse\u002Facid-base-essentials\">Acid-Base Essentials\u003C\u002Fa> course.\u003C\u002Fp>",{"type":239,"data":240},"cta",{"readDurationInSeconds":241,"text":242,"buttonText":243,"buttonUrl":244},3.466666666666667,"Become a great clinician with our video courses and workshops","Start learning for free","https:\u002F\u002Fwww.medmastery.com\u002Fuser\u002Fregister",{"type":229,"data":246},{"readDurationInSeconds":247,"title":248,"text":249},42.666666666666664,"Video transcript","\u003Cp>Another form of abnormal ventilation perfusion relationship can be seen as a result of alveolar units with ventilation, but no persistent perfusion. Conceptually, any alveolar units with v Q greater than one, but not infinity, can be described as if the units were functionally equivalent to areas of Deadspace.\u003C\u002Fp>\u003Cp>Areas of high v Q or physiologic Deadspace represent regions of wasted ventilation as far as carbon dioxide elimination is concerned. However, in most disorders characterized by an increase in lung areas with high v Q hypercapnia does not occur. These individuals can compensate for the increase in Dead Space by increasing the overall level of ventilation to keep pa co2 constant.\u003C\u002Fp>\u003Cp>So, an elevation in arterial carbon dioxide tension would only be seen when the patient can't sustain the overall level of ventilation necessary to compensate. So, I hope you liked this video. Absolutely, make sure to check out the course this video was taken from and to register for a free trial account which will give you access to select the chapters of the course. 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Learn how to treat mild and moderate COPD exacerbations—and when to escalate care.",{"alt":335,"title":289,"size":336,"location":337},"Older patient using a handheld nebulizer to inhale bronchodilator medication during an acute COPD exacerbation",{"width":318,"height":318},{"bucket":293,"key":338},"\u002F2026-04\u002FC133(4)_ exacerbations_magazine image.png",{"id":340,"title":341,"relativeURL":342,"image":343,"professionLong":344,"profession":345,"weight":347},5365,"Siamak Moayedi, MD","\u002Fteachers\u002Fsiamak-moayedi-md","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cf02-1064-4074-817b-0eb5de6ded74","Professor and Director of Medical Student Education, University of Maryland and Course Director, Essential and Critical Procedures, Emergency Medicine.",{"name":346},"Emergency medicine physician",1533,"\u002Fmagazine\u002Facute-copd-exacerbation-treatment",191,"4m",{"created":352,"updated":353,"published":354},1776705362,1776710540,1776710541,{"seo":356,"og":358},{"title":357,"description":213},"What defines physiological dead space? | Medmastery",{"title":357,"description":213,"image":359},{"alt":289,"title":289,"size":360,"location":363},{"width":361,"height":362},606,364,{"bucket":293,"key":364},"\u002Fmigrated-images\u002Fblood-gas-mag-preview-5_3-2x.png",{"id":366,"created":367,"updated":368,"published":367},342,1587208228,1655189586]