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enseignants",{"title":54,"url":55},{"title":57,"url":58},{"title":186,"group":48,"menu":187},"Produit",[188,189,190,191,192,193,194],{"title":38,"url":7},{"title":65,"url":66},{"title":68,"url":69},{"title":71,"url":72},{"title":74,"url":75},{"title":15,"url":77},{"title":195,"url":10},"Tarification",{"title":197,"group":48,"menu":198},"Mentions légales",[199,200,201,202,203],{"title":197,"url":84},{"title":86,"url":87},{"title":89,"url":90},{"title":92,"url":93},{"title":95,"url":96},{"title":205,"group":48,"menu":206},"Service client",[207,208,209],{"title":101,"url":102},{"title":104,"url":105},{"title":107,"url":108},{"content":211,"related":295,"meta":366,"internal":378},{"title":212,"leadIn":213,"category":214,"elements":217,"becomeAnExpert":247,"author":284,"readDuration":293,"readDurationFormatted":294},"Setting up the Crono® APO-go® and PAR apomorphine infusion pumps","Apomorphine infusion pumps deliver continuous Parkinson’s therapy when oral medication no longer provides stable symptom control. See how to get Crono APO-go and Crono PAR  pumps ready for infusion in Parkinson’s care.",{"id":215,"name":216},1,"Course previews",[218,229,234,242],{"type":219,"data":220},"video",{"readDurationInSeconds":221,"video":222},320,{"platform":223,"name":224,"url":225,"size":226},"YouTube","Apomorphine infusion pumps: Crono APO-go and Crono PAR explained | Treatment of Parkinson’s disease","https:\u002F\u002Fyoutu.be\u002FlN1rW3-nu-A",{"width":227,"height":228},200,113,{"type":230,"data":231},"free_text",{"readDurationInSeconds":232,"text":233},56.53333333333333,"\u003Cp>When oral Parkinson’s medications can no longer keep symptoms steady, continuous subcutaneous apomorphine infusion helps smooth motor fluctuations throughout the day. The Crono APO-go and Crono PAR pumps deliver apomorphine continuously for more consistent symptom control.\u003C\u002Fp>\u003Cp>This video from our Administering Parkinson’s Therapy with Pumps and Pens series walks you through the complete setup—showing how to prepare, fill, and start each device.\u003C\u002Fp>\u003Cp>You’ll learn how to:\u003C\u002Fp>\u003Cul>\u003Cli data-list-item-id=\"e9043a7ae87905bced1998b74c18c40b5\">Choose the appropriate syringe size and apomorphine concentration\u003C\u002Fli>\u003Cli data-list-item-id=\"ed3c91e5a363b5227bb14434ca8252889\">Program dosing flow rates\u003C\u002Fli>\u003Cli data-list-item-id=\"e567ec6ab9bcb9797641b5920b312224e\">Assemble and connect the syringe, adapter, and infusion line\u003C\u002Fli>\u003Cli data-list-item-id=\"ead92a062e90acf7743b659798d945ce1\">Prepare and secure a subcutaneous injection site\u003C\u002Fli>\u003Cli data-list-item-id=\"e872b6363a0aeba3715caf4050f92ed7d\">Start the infusion and confirm operation\u003C\u002Fli>\u003C\u002Ful>\u003Cp>This lesson provides a clear, step-by-step walkthrough of setting up the Crono APO-go and Crono PAR apomorphine infusion pumps for continuous Parkinson’s therapy.\u003C\u002Fp>\u003Ch3>Master device-assisted therapy for advanced Parkinson's disease\u003C\u002Fh3>\u003Cp>Wearing-off phenomenon between medication doses can be one of the more challenging aspects of advanced Parkinson's management. This 6-part video series gives you a practical framework for when and how to use device-assisted therapies—from infusions to injections—so you can act with confidence: \u003C\u002Fp>\u003Cp>1. \u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fmagazine\u002Fd-mine-pump-setup\">How to set up the D-mine® apomorphine pump\u003C\u002Fa> \u003C\u002Fp>\u003Cp>2. \u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fmagazine\u002Fstarting-so-connect-apomorphine-pump\">\u003Cspan>How to prepare and start the SO-CONNECT\u003Csup>TM\u003C\u002Fsup> subcutaneous apomorphine pump\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan>   \u003C\u002Fspan> \u003C\u002Fp>\u003Cp>3. Setting up the Crono® APO-go® and PAR apomorphine infusion pumps   \u003C\u002Fp>\u003Cp>4. \u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fmagazine\u002FAPO-go-POD-easy-infusion-setup\">APO-go® POD: the EASY apomorphine infusion setup\u003C\u002Fa>\u003C\u002Fp>\u003Cp>5. \u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fmagazine\u002Fduodopa-pump-vs-crono-lecig-levodopa-infusion\">2 Levodopa infusion setups: Duodopa® pump vs Crono® LECIG\u003C\u002Fa>\u003C\u002Fp>\u003Cp>6. \u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fmagazine\u002Fapomorphine-pen-injector-setup\">Using an apomorphine pen injector when medications wear off\u003C\u002Fa>\u003C\u002Fp>",{"type":235,"data":236},"cta",{"readDurationInSeconds":237,"text":238,"buttonText":239,"buttonUrl":240,"teachIllustration":241},4,"Start the first chapter of our Parkinson's Masterclass: Advanced Therapeutics course for free","Start chapter 1 now","https:\u002F\u002Fwww.medmastery.com\u002Fuser\u002Fregister?target=%2Fcourses%2Fparkinsons-masterclass-advanced-therapeutics","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9ab1a4dc-b2e8-4a53-86a4-1f1d531e4aee",{"type":230,"data":243},{"readDurationInSeconds":244,"title":245,"text":246},109.6,"Transcript","\u003Ch3>Overview of Crono Crono APO-go and Crono PAR apomorphine infusion pumps\u003C\u002Fh3>\u003Cp>[00:00]\u003Cbr>The Crono APO-go and Crono PAR pumps are manual syringe drivers used for the continuous subcutaneous infusion of apomorphine. They are compatible with 20 and 50 mL syringes. The choice between these syringe sizes can depend on factors such as the patient’s specific medication needs, dosage requirements, and duration of infusion.\u003C\u002Fp>\u003Ch3>Apomorphine syringe options and concentration settings\u003C\u002Fh3>\u003Cp>[00:23]\u003Cbr>The 50 mL syringe can be filled with 13 different concentrations of apomorphine, allowing the dose to be individually tailored to the patient and helping to avoid possible skin reactions that can occur with higher concentrations. The dose is programmed in milliliters, and a conversion table is used to convert milligrams to milliliters.\u003C\u002Fp>\u003Ch3>Apomorphine dosing and flow rate programming\u003C\u002Fh3>\u003Cp>[00:46]\u003Cbr>For example, the 50 mL syringe is filled with four apomorphine prefilled syringes and 10 mL of sodium chloride. A flow rate from 6 a.m. to 12 p.m. should be 6 mg\u002Fhour. The concentration is 4 mg\u002FmL, and the flow rate in mL\u002Fhour is then 1.5 mL\u002Fhour. Up to three different flow rates can be programmed, as well as a bolus dose for extra doses throughout the day. The programmed values can be locked so the patient can’t change them.\u003C\u002Fp>\u003Ch3>Preparing the Crono apomorphine infusion pumps\u003C\u002Fh3>\u003Cp>[01:27]\u003Cbr>The pump is powered by a battery. Before setting up the pump, disinfect your hands and work surface. Place all of your materials on the table, including a special tray to hold all of the materials, the Crono APO-go and Crono PAR pump, apomorphine in prefilled syringes, a plastic medication syringe, an infusion set, an adapter, and tape. \u003C\u002Fp>\u003Ch3>Preparing the syringe and pump assembly\u003C\u002Fh3>\u003Cp>[02:05]\u003Cbr>Place the pump in the tray. Open the plastic syringe package, and then pull the stopper out and push it back in once to loosen it. Unscrew the plunger to remove it from the syringe. Place the syringe on the pump and turn it to connect the syringe to the pump. Now screw the adapter onto the syringe.\u003C\u002Fp>\u003Ch3>Filling the pump syringe with apomorphine\u003C\u002Fh3>\u003Cp>[02:42]\u003Cbr>Take the syringe prefilled with apomorphine, place it on the adapter, and slowly fill the plastic syringe. Repeat this step with a second syringe prefilled with apomorphine to fill the 20 mL plastic syringe with the medication. Now remove the adapter and screw the infusion line onto the plastic syringe.\u003C\u002Fp>\u003Ch3>Preparing the injection site\u003C\u002Fh3>\u003Cp>[03:43]\u003Cbr>Disinfect the injection site—so the lower abdomen, inner thigh, upper arm, under the shoulder blades, or in the flanks. Insert the needle at the injection site and remove the grip on the back. Secure the needle and line with tape.\u003C\u002Fp>\u003Ch3>Starting the apomorphine pump infusion\u003C\u002Fh3>\u003Cp>[04:09]\u003Cbr>Press the on\u002Foff button to start the infusion. You will hear a beep once it’s started. The patient can give themselves an extra dose directly after preparing the pump by pressing the d\u002FP button. The infusion line does not have to be primed because this is a subcutaneous application, and a dry needle protects against skin irritation. Finally, put the pump in the carrying bag.\u003Cbr> \u003C\u002Fp>",{"courses":248,"showAwardsBelow":48},[249,268],{"id":250,"isFreeCmeCourse":251,"title":252,"type":253,"specialization":254,"teachers":256,"cmeCredits":237,"teacherIllustration":258,"backgroundImage":259,"relativeUrl":260,"lastChanged":261,"created":262,"description":263,"relativeURL":260,"meta":264},13549,false,"Parkinson's Essentials","course",[255],"Neurology and Psychiatry",[257],"Kara J. Wyant, MD","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9aa38ffc-3b1a-4f77-ad90-d234653a550e","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9aa38ffd-449f-4211-9f27-adb0b632bb59","\u002Fcourses\u002Fparkinsons-essentials","1774294684","1702943539","How confident are you in your ability to differentiate Parkinson’s disease from its look-alikes and correctly diagnose it? There is a gap in comprehensive training related to this complex disease and we are excited to bring you up to speed! Dive into this course as we cover pathophysiology, evaluate common motor and non-motor symptoms, learn how to initiate the best therapy, and more!",{"duration":265,"quizzes":266,"lessons":267},9878,5,41,{"id":269,"isFreeCmeCourse":251,"title":270,"type":253,"specialization":271,"teachers":272,"cmeCredits":274,"teacherIllustration":241,"backgroundImage":275,"relativeUrl":276,"lastChanged":277,"created":278,"description":279,"relativeURL":276,"meta":280},13653,"Parkinson's Masterclass: Advanced Therapeutics",[255],[273],"Kelvin L. Chou, MD",3.5,"https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9ab1a4dd-cdb3-463f-941f-441f5f7e0c81","\u002Fcourses\u002Fparkinsons-masterclass-advanced-therapeutics","1775517399","1706570643","Explore cutting-edge Parkinson’s treatments, including device-assisted and lesioning therapies. From deep brain stimulation to MRI-guided focused ultrasound and levodopa-carbidopa intestinal gel, discover the ideal therapy for each patient. Learn to discuss therapeutic options, titrate treatments confidently, and navigate potential side effects. Elevate your expertise in Parkinson's care today!",{"duration":281,"quizzes":282,"lessons":283},7176,6,36,{"id":285,"name":286,"image":287,"profession":288,"relativeUrl":291,"specializations":292},13760,"Nicole Pohlschmidt","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cf03-4fc8-4d9c-9bfd-67d8d8df4e89",{"name":289,"description":290},"Qualified nurse","Nurse specialized in Parkinson’s therapeutic applications","\u002Fteachers\u002Fnicole-pohlschmidt",[],181,"4m",[296,323,342],{"id":297,"title":298,"text":299,"image":300,"author":308,"path":316,"readDuration":317,"readDurationFormatted":318,"internal":319},1350,"How to Recognize INOCA (ANOCA) on an Exercise Stress Test ","Angina, abnormal stress test, clean coronaries—that's INOCA (or ANOCA), and it carries real risk. Learn to recognize and report it with exercise stress ECG.",{"alt":301,"title":302,"size":303,"location":305},"Illustration of the heart's coronary vasculature showing large coronary arteries and the extensive network of smaller vessels affected in INOCA (ischemia with nonobstructive coronary arteries).","",{"width":304,"height":304},1200,{"bucket":306,"key":307},"public-drupal-medmastery-assets-production","\u002F2026-05\u002FC17(1)_magazine image_0.png",{"id":309,"title":310,"relativeURL":311,"image":312,"professionLong":313,"profession":314,"weight":237},1563,"Franz Wiesbauer, MD MPH","\u002Fteachers\u002Ffranz-wiesbauer-md-mph","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cef0-41ee-4005-9e4a-d8711c816401","Franz is the founder and CEO of Medmastery. 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Learn who to screen and when, which measures to request, and how to stratify risk.",{"alt":328,"title":302,"size":329,"location":331},"Lipid panel blood sample tubes used to test for hyperlipidemia in a laboratory setting",{"width":330,"height":330},600,{"bucket":306,"key":332},"\u002F2026-04\u002FC121_magazine image.png",{"id":309,"title":310,"relativeURL":311,"image":312,"professionLong":313,"profession":334,"weight":237},{"name":315},"\u002Fmagazine\u002Ftest-for-hyperlipidemia",246,"5m",{"created":339,"updated":340,"published":341},1777403036,1777572381,1777412421,{"id":343,"title":344,"text":345,"image":346,"author":351,"path":360,"readDuration":361,"readDurationFormatted":294,"internal":362},1347,"Outpatient care for COPD exacerbations","Most acute COPD exacerbations can be managed with outpatient treatment. Learn how to treat mild and moderate COPD exacerbations—and when to escalate care.",{"alt":347,"title":302,"size":348,"location":349},"Older patient using a handheld nebulizer to inhale bronchodilator medication during an acute COPD exacerbation",{"width":330,"height":330},{"bucket":306,"key":350},"\u002F2026-04\u002FC133(4)_ exacerbations_magazine image.png",{"id":352,"title":353,"relativeURL":354,"image":355,"professionLong":356,"profession":357,"weight":359},5365,"Siamak Moayedi, MD","\u002Fteachers\u002Fsiamak-moayedi-md","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cf02-1064-4074-817b-0eb5de6ded74","Professor and Director of Medical Student Education, University of Maryland and Course Director, Essential and Critical Procedures, Emergency Medicine.",{"name":358},"Emergency medicine physician",1533,"\u002Fmagazine\u002Facute-copd-exacerbation-treatment",191,{"created":363,"updated":364,"published":365},1776705362,1776710540,1776710541,{"seo":367,"og":370},{"title":368,"description":369},"Apomorphine infusion pumps: Crono APO-go and Crono PAR | Medmastery","See how to prepare and program the Crono APO-go and Crono PAR apomorphine infusion pumps for continuous subcutaneous therapy in Parkinson’s care.",{"title":371,"description":372,"image":373},"Preparing Crono APO-go and PAR pumps | Medmastery","See how easy it is to use the Crono APO-go and PAR pumps, manual syringe drivers used for continuous apomorphine infusion in Parkinson’s therapy.",{"alt":374,"title":302,"size":375,"location":376},"Crono APO-go apomorphine infusion pump with attached syringe for continuous subcutaneous infusion.",{"width":330,"height":330},{"bucket":306,"key":377},"\u002F2026-02\u002FCrono APO-go and Crono PAR pump@0.5x.png",{"id":379,"created":380,"updated":381,"published":382},1337,1770139499,1774898168,1770232039]