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always an accurate reflection of kidney function. ",{"id":215,"name":216},1,"Course previews",[218,228,233,238,246],{"type":219,"data":220},"video",{"readDurationInSeconds":221,"video":222},124,{"platform":223,"name":212,"url":224,"size":225},"YouTube","https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=KQvHP4yRmNU",{"width":226,"height":227},200,113,{"type":229,"data":230},"free_text",{"readDurationInSeconds":231,"text":232},11.2,"\u003Cp>A normal plasma creatinine level does not necessarily mean that renal function is normal. In this video, from our \u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fcourse\u002Fkidney-function-test-essentials\" target=\"_blank\">Kidney Function Test Essentials\u003C\u002Fa> course, we'll take a look at the physiology of creatinine, what we need to consider when interpreting creatinine levels, and why GFR is not always an accurate reflection of kidney function. \u003C\u002Fp>",{"type":229,"data":234},{"readDurationInSeconds":235,"title":236,"text":237},19.733333333333334,"Join our Kidney Function Test Essentials course now!","\u003Cp>Master the ins and outs of kidney function tests! Order and interpret these tests with complete confidence, knowing that you’ve conquered this critical skill. Taking a shotgun approach to kidney function testing can be tempting if nephrology isn't your forte. By the end of this course, however, you’ll be comfortable ordering and interpreting all of the common kidney function tests. You’ll understand the clinical implications of abnormalities seen on these tests and be able to form a practical plan of action.\u003C\u002Fp>",{"type":239,"data":240},"cta",{"readDurationInSeconds":241,"text":242,"buttonText":243,"buttonUrl":244,"teachIllustration":245},4,"Start the first chapter of our Kidney Function Test Essentials course for free","Start chapter 1 now","https:\u002F\u002Fwww.medmastery.com\u002Fuser\u002Fregister?target=%2Fcourses%2Fkidney-function-test-essentials","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F99f55f12-b643-4563-bc42-5173e3289443",{"type":229,"data":247},{"readDurationInSeconds":248,"title":249,"text":250},43.199999999999996,"Video transcript","\u003Cp>Creatine is synthesized in the kidneys, liver and pancreas. It is transported in the blood to other organs, especially brain and muscle, where it is phosphorylated to phosphocreatine. Phosphocreatine is a high energy compound, an interconversion of phosphocreatine to creatine is important to muscle function. Creatinine is the waste product derived from creatine and phosphocreatine.\u003C\u002Fp>\u003Cp>Creatine in production is related to the muscle mass of an individual. The higher the muscle mass, the greater the creatine in production. Women usually excrete 1.2 grams of creatinine per day, while men excrete 1.5 grams per day. Serum creatinine levels are affected by gender, age, weight, lean body mass and dietary protein intake.\u003C\u002Fp>\u003Cp>Creatinine is filtered and excreted by the kidney, so plasma creatinine is inversely related to the glomerular filtration rate, or GFR. However, GFR can decrease by up to 50 percent before plasma creatinine concentration rises above the normal range. 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Amer Wahed, MD FRCPath",2,"https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F99f55f13-9066-41ba-a235-c2a2e0596ff7","\u002Fcourses\u002Fkidney-function-test-essentials","1766826870","1619391919","Taking a shotgun approach to renal function testing can be tempting if nephrology is not your forte. By the end of this course, however, you will be comfortable ordering and interpreting common renal function tests and will know exactly which test to order, every time. 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Learn to recognize and report it with exercise stress ECG.",{"alt":290,"title":291,"size":292,"location":294},"Illustration of the heart's coronary vasculature showing large coronary arteries and the extensive network of smaller vessels affected in INOCA (ischemia with nonobstructive coronary arteries).","",{"width":293,"height":293},1200,{"bucket":295,"key":296},"public-drupal-medmastery-assets-production","\u002F2026-05\u002FC17(1)_magazine image_0.png",{"id":298,"title":299,"relativeURL":300,"image":301,"professionLong":302,"profession":303,"weight":241},1563,"Franz Wiesbauer, MD MPH","\u002Fteachers\u002Ffranz-wiesbauer-md-mph","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cef0-41ee-4005-9e4a-d8711c816401","Franz is the founder and CEO of Medmastery. 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Learn who to screen and when, which measures to request, and how to stratify risk.",{"alt":317,"title":291,"size":318,"location":320},"Lipid panel blood sample tubes used to test for hyperlipidemia in a laboratory setting",{"width":319,"height":319},600,{"bucket":295,"key":321},"\u002F2026-04\u002FC121_magazine image.png",{"id":298,"title":299,"relativeURL":300,"image":301,"professionLong":302,"profession":323,"weight":241},{"name":304},"\u002Fmagazine\u002Ftest-for-hyperlipidemia",246,"5m",{"created":328,"updated":329,"published":330},1777403036,1777572381,1777412421,{"id":332,"title":333,"text":334,"image":335,"author":340,"path":349,"readDuration":350,"readDurationFormatted":351,"internal":352},1347,"Outpatient care for COPD exacerbations","Most acute COPD exacerbations can be managed with outpatient treatment. Learn how to treat mild and moderate COPD exacerbations—and when to escalate care.",{"alt":336,"title":291,"size":337,"location":338},"Older patient using a handheld nebulizer to inhale bronchodilator medication during an acute COPD exacerbation",{"width":319,"height":319},{"bucket":295,"key":339},"\u002F2026-04\u002FC133(4)_ exacerbations_magazine image.png",{"id":341,"title":342,"relativeURL":343,"image":344,"professionLong":345,"profession":346,"weight":348},5365,"Siamak Moayedi, MD","\u002Fteachers\u002Fsiamak-moayedi-md","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cf02-1064-4074-817b-0eb5de6ded74","Professor and Director of Medical Student Education, University of Maryland and Course Director, Essential and Critical Procedures, Emergency Medicine.",{"name":347},"Emergency medicine physician",1533,"\u002Fmagazine\u002Facute-copd-exacerbation-treatment",191,"4m",{"created":353,"updated":354,"published":355},1776705362,1776710540,1776710541,{"seo":357,"og":359},{"title":358,"description":213},"Measuring serum creatinine | Medmastery",{"title":358,"description":213,"image":360},{"alt":291,"title":291,"size":361,"location":364},{"width":362,"height":363},606,364,{"bucket":295,"key":365},"\u002Fmigrated-images\u002F01-Measuring-serum-creatinine.png",{"id":367,"created":368,"updated":369,"published":368},399,1618333035,1655189586]