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Which of these drugs does nirmatrelvir \u002F ritonavir interact with?",[215,221,226,239],{"type":216,"data":217},"free_text",{"readDurationInSeconds":218,"title":219,"text":220},15.466666666666667,"Pop Quiz: December 12, 2024","\u003Cdiv>\u003Cdiv>\u003Cdiv>\u003Cp>\u003Cstrong>A 61-year-old female reports with rectal bleeding, muscle aches, and fatigue. She’s been taking the first-line COVID treatment nirmatrelvir \u002F ritonavir for 4 days. Which of her medications have a drug-drug interaction with nirmatrelvir \u002F ritonavir that should have been addressed before she began taking nirmatrelvir \u002F ritonavir?\u003C\u002Fstrong>\u003Cbr>\u003Cbr>A\u003Cem>. \u003C\u002Fem>Liraglutide\u003C\u002Fp>\u003Cp>B\u003Cem>. \u003C\u002Fem>Metformin\u003C\u002Fp>\u003Cp>C\u003Cem>. \u003C\u002Fem>Metoprolol succinate\u003C\u002Fp>\u003Cp>D\u003Cem>. \u003C\u002Fem>Rivaroxaban\u003C\u002Fp>\u003C\u002Fdiv>\u003Cdiv>\u003Cp>\u003Cspan lang=\"EN-US\">\u003C\u002Fspan>\u003Cspan> \u003C\u002Fspan>\u003C\u002Fp>\u003C\u002Fdiv>\u003C\u002Fdiv>\u003C\u002Fdiv>",{"type":216,"data":222},{"readDurationInSeconds":223,"title":224,"text":225},27.2,"Check your answer!","\u003Cp>\u003Cstrong>The correct answer is D. Rivaroxaban\u003C\u002Fstrong>\u003Cbr>\u003Cbr> \u003Cstrong>Explanation:\u003C\u002Fstrong>\u003Cbr>\u003Cbr>\u003Cspan>Gastrointestinal bleeding is always a risk factor with the use of direct oral anticoagulants\u003C\u002Fspan>\u003Cstrong> \u003C\u002Fstrong>(\u003Cspan>DOACs for short).\u003C\u002Fspan>\u003Cbr>\u003Cbr>S\u003Cspan>he is taking liraglutide 1.8 mg \u002F day for diabetes, metformin 1000 mg \u002F day for diabetes, metoprolol succinate 100 mg \u002F day for hypertension and rate control, and rivaroxaban 15 mg \u002F day for nonvalvular atrial fibrillation.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan>Use of the University of Liverpool’s drug-drug interaction checker, or another similar checker, should have helped you to determine that there are potential interactions with nirmatrelvir \u002F ritonavir and rivaroxaban that should have been addressed prior to rivaroxaban being prescribed.\u003C\u002Fspan>\u003Cbr>\u003Cbr>\u003Cspan>Liraglutide, metformin, and metoprolol succinate don’t interact with nirmatrelvir \u002F ritonavir.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp> \u003C\u002Fp>\u003Cp>\u003Cem>References:\u003C\u002Fem>\u003C\u002Fp>\u003Cp>\u003Cspan>Liverpool DDI Checker. 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