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previews",[218,229,234,239,246],{"type":219,"data":220},"video",{"readDurationInSeconds":221,"video":222},100,{"platform":223,"name":224,"url":225,"size":226},"YouTube","How amiodarone affects thyroid function.","https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=d1pSXnWWE48",{"width":227,"height":228},200,113,{"type":230,"data":231},"free_text",{"readDurationInSeconds":232,"text":233},10.133333333333333,"\u003Cp>Patients using amiodarone can exhibit symptoms of thyroid dysfunction years after commencing therapy. In this video, you'll find out how amiodarone affects thyroid function, when this effect stabilizes, and how often you should monitor the lab results of patients using amiodarone.\u003C\u002Fp>",{"type":230,"data":235},{"readDurationInSeconds":236,"title":237,"text":238},13.6,"Join our Thyroid Disease Masterclass today!","\u003Cp>Master the management of thyroid disease in our \u003Cstrong>\u003Ca href=\"https:\u002F\u002Fwww.medmastery.com\u002Fcourse\u002Fthyroid-disease-masterclass\">Thyroid Disease Masterclass\u003C\u002Fa>.\u003C\u002Fstrong> Dr. Tracy Tylee–Clinical Assistant Professor of Endocrinology at the University of Washington–will review the pathophysiology of thyroid dysfunction, discuss the interpretation of thyroid tests, explain how pregnancy and certain medications can alter thyroid function, and evaluate the best treatment options.\u003C\u002Fp>",{"type":240,"data":241},"cta",{"readDurationInSeconds":242,"text":243,"buttonText":244,"buttonUrl":245},3.466666666666667,"Become a great clinician with our video courses and workshops","Start learning for free","https:\u002F\u002Fwww.medmastery.com\u002Fuser\u002Fregister",{"type":230,"data":247},{"readDurationInSeconds":248,"title":249,"text":250},55.73333333333333,"Video Transcript","\u003Cp dir=\"ltr\">\u003Cstrong>[00:00:00] \u003C\u002Fstrong>Amiodarone can have a number of different effects on thyroid function including on thyroid hormone production and thyroid hormone action. Some of these effects can alter the results of our thyroid labs. Amiodarone blocks the conversion of T4 to T3, which results in low T3 levels and slightly higher T4 levels. This leads to a decrease in inhibition at the pituitary due to the low levels of T3, which leads to an increase in TSH levels. So, initial labs for \u003C\u002Fp>\u003Cp dir=\"ltr\">\u003Cstrong>[00:00:30] \u003C\u002Fstrong>patients starting on amiodarone therapy will show an elevation in TSH, with a low T3, and a slightly elevated T4. Over time, the increased TSH leads to increase in T4 production. The higher levels of T4 are able to overcome that blockade of amiodarone and convert to adequate levels of T3. This increases inhibition at the level of the pituitary and TSH levels return to normal. So, after several months of amiodarone therapy, patient's labs will show a normal \u003C\u002Fp>\u003Cp dir=\"ltr\">\u003Cstrong>[00:01:00]\u003C\u002Fstrong> TSH, with a high T4 but a T3 that's at the low end of normal. In addition to the changes in thyroid labs, amiodarone can have a number of different effects on thyroid function. While many patients will maintain normal thyroid function on amiodarone, some patients will develop thyroid dysfunction months or years into therapy. Thus, it is important that patients who are on amiodarone therapy are appropriately monitored for thyroid function. At baseline, all patients should have a TSH and free thyroid hormone levels measured, and this should be repeated at three months. \u003C\u002Fp>\u003Cp dir=\"ltr\">\u003Cstrong>[00:01:30] \u003C\u002Fstrong>While patients are on amiodarone therapy, they should have a TSH checked every six months, to ensure that their thyroid function remains normal while on therapy.\u003C\u002Fp>",{"courses":252,"showAwardsBelow":48},[253],{"id":254,"isFreeCmeCourse":255,"title":256,"type":257,"specialization":258,"teachers":260,"cmeCredits":262,"teacherIllustration":263,"backgroundImage":264,"relativeUrl":265,"lastChanged":266,"created":267,"description":268,"relativeURL":265,"meta":269},3749,false,"Thyroid Disease Masterclass","course",[259],"Endocrinology",[261],"Tracy Tylee, MD",3,"https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F99f55f0f-1e9c-413b-a826-11c1e0ec9808","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F99f55f0f-e1ca-46d7-9d36-ce0e3d322f8b","\u002Fcourses\u002Fthyroid-disease-masterclass","1767867649","1499852541","Using simple illustrations and elegant animations, we review the pathophysiology of thyroid dysfunction, discuss the interpretation of thyroid tests, explain how pregnancy and certain medications can alter thyroid function, and evaluate the best treatment options—this course will prepare you to confidently assess and effectively manage patients with thyroid disease.",{"duration":270,"quizzes":271,"lessons":272},5383,9,56,{"id":274,"name":261,"image":275,"profession":276,"relativeUrl":279,"specializations":280},3748,"https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cefc-88e6-4632-a711-cf90c6d98c24",{"name":277,"description":278},"Endocrinologist","Tracy is an Associate Professor of Endocrinology at the University of Washington, and Program Director for the Endocrinology Fellowship Program.","\u002Fteachers\u002Ftracy-tylee-md",[259],88,"2m",[284,312,331],{"id":285,"title":286,"text":287,"image":288,"author":296,"path":305,"readDuration":306,"readDurationFormatted":307,"internal":308},1352,"Injectable cholesterol medication: using PCSK9 inhibitors","Not all patients reach their LDL targets with oral therapy. Learn when injectable cholesterol medication helps and how PCSK9 inhibitors work.",{"alt":289,"title":290,"size":291,"location":293},"Two PCSK9 inhibitor autoinjector pens—an injectable cholesterol medication—shown on a light blue background.","",{"width":292,"height":292},900,{"bucket":294,"key":295},"public-drupal-medmastery-assets-production","\u002F2026-05\u002FC121(3)_magazine image.png",{"id":297,"title":298,"relativeURL":299,"image":300,"professionLong":301,"profession":302,"weight":304},1563,"Franz Wiesbauer, MD MPH","\u002Fteachers\u002Ffranz-wiesbauer-md-mph","https:\u002F\u002Fmedmastery-backend-prod-kjbeds.s3.eu-west-1.amazonaws.com\u002Fmedia\u002Fimages\u002F9c43cef0-41ee-4005-9e4a-d8711c816401","Franz is the founder and CEO of Medmastery. He is an internist with a specialization in cardiology and a master’s in public health from Johns Hopkins University.",{"name":303},"Internist",4,"\u002Fmagazine\u002Fpcsk9-injectable-cholesterol-medication",279,"5m",{"created":309,"updated":310,"published":311},1779483663,1779495630,1779495631,{"id":313,"title":314,"text":315,"image":316,"author":322,"path":324,"readDuration":325,"readDurationFormatted":326,"internal":327},1351,"Starting statins as first-line therapy for hyperlipidemia","Starting statins: how to choose the right agent for your patient, match statin intensity to cardiovascular risk, and monitor effectively after initiation.",{"alt":317,"title":290,"size":318,"location":320},"Healthcare provider discussing starting statins with a patient and reviewing a medication bottle",{"width":319,"height":319},660,{"bucket":294,"key":321},"\u002F2026-05\u002FC121(2)_magazine image.png",{"id":297,"title":298,"relativeURL":299,"image":300,"professionLong":301,"profession":323,"weight":304},{"name":303},"\u002Fmagazine\u002Fstarting-statins-first-line-therapy",238,"4m",{"created":328,"updated":329,"published":330},1778960150,1779196374,1778961827,{"id":332,"title":333,"text":334,"image":335,"author":341,"path":343,"readDuration":344,"readDurationFormatted":345,"internal":346},1350,"How to recognize INOCA (ANOCA) on an exercise stress test ","Angina, abnormal stress test, clean coronaries—that's INOCA (or ANOCA), and it carries real risk. Learn to recognize and report it with exercise stress ECG.",{"alt":336,"title":290,"size":337,"location":339},"Illustration of the heart's coronary vasculature showing large coronary arteries and the extensive network of smaller vessels affected in INOCA (ischemia with nonobstructive coronary arteries).",{"width":338,"height":338},1200,{"bucket":294,"key":340},"\u002F2026-05\u002FC17(1)_magazine image_0.png",{"id":297,"title":298,"relativeURL":299,"image":300,"professionLong":301,"profession":342,"weight":304},{"name":303},"\u002Fmagazine\u002Fexercise-stress-ecg-inoca",141,"3m",{"created":347,"updated":348,"published":349},1778115738,1778799792,1778118255,{"seo":351,"og":353},{"title":352,"description":213},"How amiodarone affects thyroid function | Medmastery",{"title":352,"description":213,"image":354},{"alt":290,"title":290,"size":355,"location":358},{"width":356,"height":357},790,440,{"bucket":294,"key":359},"\u002Fmigrated-images\u002FScreen Shot 2018-03-14 at 1.22.05 pm.png",{"id":361,"created":362,"updated":363,"published":362},198,1521030503,1655189586]